A lymph node–targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2
نویسندگان
چکیده
Lymph node–targeting adjuvant AMP-CpG enhances SARS-CoV-2 RBD vaccine-induced cellular and humoral immune responses.
منابع مشابه
A 219-mer CHO-expressing receptor-binding domain of SARS-CoV S protein induces potent immune responses and protective immunity.
Development of vaccines is essential for the prevention of future recurrences of severe acute respiratory syndrome (SARS), caused by the SARS coronavirus (SARS-CoV). The spike (S) protein, especially receptor-binding domain (RBD) of SARS-CoV, plays important roles in the prevention of SARS infection, and is thus an important component in SARS vaccine development. In this study, we expressed a 2...
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ژورنال
عنوان ژورنال: Science Advances
سال: 2021
ISSN: ['2375-2548']
DOI: https://doi.org/10.1126/sciadv.abe5819